Evidence Synthesis @CRSU

HPV Self-Sampling for Cervical Cancer Screening: A Rapid Review

• Commissioned by the National Screening Committee and is expected to complete at the end of 2024. 

Regional anaesthesia for reducing the incidence and severity of chronic pain after surgery: A living systematic review and network meta-analysis.

• Commenced in May 2024 and expected to complete in April 2025. This review also includes a study within a review (SWAR) on Use of AI for extraction of outcome data

Review of modelling studies and cost-effectiveness analyses for UK cancer screening programmes

• Commisioned by the National Screening Committee  and commenced October 2024. Expected to complete in February 2025

What are effective and safe pharmacological and non-pharmacological interventions for managing insomnia and sleep fragmentation in children with moderate to severe cerebral palsy?

• Commissoned by the James Lind Alliance. Expected to commence November 2024

UK NSC Position Statement: Incidental Findings in Economic Evaluation of Screening Programmes

• Commissioned by the National Screening Committee in September 2024 this is a follow on piece of work from the review completed in 2023. Expected to complete in March 2025. 

At What Levels of Expected Blood Loss from Surgery is Tranexamic Acid (TXA) Effective at Reducing the Need for Blood Transfusion?

• Commissioned by NICE, this project is expected to complete in November 2024.

Prognostic Accuracy of Prediction Tools for Surgical Bleeding Risk

• Commissioned by NICE, the manuscript for this project is currently awaiting acceptance to a peer reviewed journal. 
• Plain Language Summary - Blood loss prediction tools  

Defining Incidental Findings in Economic Evaluations of Screening Programmes: a Scoping Review

• This project was commissioned by the National Screening Centre. The final report was delivered in November 2023. 

• Plain Language Summary -Incidental findings